Although urine is sterile, it has hundreds of different kinds of wastes from the body. All sorts of things affect what is in your urine, including last night’s dinner, how much water you drink, what you do for exercise, and how well your kidneys work in the first place. This experiment will show you how the kidneys work to keep your body in top shape.

Our sense of touch provides us with information that helps us to process and explore our world. Nerves play an important part in the sense of touch by being the wires that carry signals from the skin to the brain. But the body has a plan in place so that our brains don’t get overwhelmed with too much information. This plan is a lot like a blueprint for wiring a house. Just like a house has light switches and electrical outlets in strategic locations, our bodies have touch receptors of various numbers based on their location. In this lab, we will explore an arm to determine where the highest concentrations of nerves are in that limb.

How do you think animals know we’re around long before they see us? Sure, most have a powerful sense of smell, but they can also hear us first. In this activity, we are going to simulate enhanced tympanic membranes (or ear drums) by attaching styrofoam cups to your ears. This will increase the number of sound waves your ears are able to capture.

Have you ever held a plastic ruler over the edge of a desk or table and whacked the end of it? If so, you would notice a funny sound. This sound changes if you change the length of the ruler that is hanging over the edge. The sound you hear is made by the ruler’s vibrations.

In this lab, we begin to learn about sound. You know it is collected and deciphered by your ears, but did you also know that all sound is made when something vibrates? It could be a guitar string, vocal chords in your throat, or a plastic ruler that is hanging over the edge of the desk: vibrations make sound.

You know that sound comes from vibration which are picked up by the pinna (external part of the ears). Then the vibrations vibrate your tympanic membrane, which in turn vibrates the ossicles and then the cochlea. The cochlea sends information through the auditory nerve and sends it to the brain, which recognizes it as sound.

In this lab, you will testing your ability to sort and match different sounds.

Sound has the ability to travel through the states of matter: solids, liquids, and gases. In this experiment we will study the movement of sound through these three states.

Levers are classified into three types: first class, second class, or third class. Their class is identified by the location of the load, the force moving the load, and the fulcrum. In this activity, you will learn about the types of levers and then use your body to make each type.

Your eyes have two different light receptors located on the back of the eyeball. These are the rods, which see black, white and grays, and the cones, which see color. In order to adapt to the dark, our eyes make a chemical called visual purple. This helps the rods to see and transmit what you see in situations where there is little light.

Your pupils also increase in diameter in the darkness. This allows for a slight increase in the amount of light entering your eye. This combination of visual purple and more light makes it possible for you to see in darker situations.

Voluntary nerves are the ones that are under our direct control. Others, called involuntary nerves, are under the control of our brains and create involuntary reactions.

Your optic nerve can be thought of as a data cord that is plugged in to each eye and connects them to your brain. The area where the nerve connects to the back of your eye creates a blind spot. There are no receptors in this area at all and if something is in that area, you won’t be able to see it. This experiment locates your blind spot.

Like sound, light travels in waves. These waves of light enter your eyes through the pupil, which is the small black dot right in the center of your colored iris. Your lens bends and focuses the light that enters your eye. In this experiment, we will study this process of bending light and we will look at the difference between concave and convex lenses.

In this lab, we are going to make an eyeball model using a balloon. This experiment should give you a better idea of how your eyes work. The way your brain actually sees things is still a mystery, but using the balloon we can get a good working model of how light gets to your brain.

This experiment not only explains how your body uses oxygen, but it is also an experiment in air pressure circles – bonus!  You will be putting a dime in a tart pan that has a bit of water in it. Then you will put a lit candle next to the dime and put a glass over the candle with the glass’s edge on the dime. Once all of the air inside the glass is used up by the candle, the dime will be easy to pick up without even getting your fingers wet! Ready to give it a try?

Everything living produces some sort of odor. Flowers use them to entice bees to pollinate them. We know that the tastes of foods are enhanced by the way that they smell. As humans, each of us even has own unique odor.

In this lab, we look at the diffusion of scents. They start in one place, but often end up spread around the room and can be detected by many people.

Peristalsis is the wavelike movement of muscles that move food through your gastrointestinal tract. The process of digestion begins with chewing and mixing the food with saliva. From there, the epiglottis opens up to deposit a hunk of chewed food (called bolus) into your esophagus – this is the tube that runs from your mouth to your stomach. Since the esophagus is so skinny, the muscles along it must expand and contract in order to move food down. In this activity we will examine that process.

We now know that odor molecules are diffused throughout a room by the motion of air molecules, which are constantly moving and bumping into them.  We also know that warm air moves faster than cold air, and that increasing the movement of the air (like with a fan) will increase the diffusion process.

In this experiment, we look at what happens when the odor molecules find their way into your nose. Your nose has smell cells located in a small area called the olfactory epithelium. We will use them here to match smells with other smells.

An oxygen and carbon dioxide exchange takes place in your bloodstream. When you breathe air into your lungs it brings in oxygen, which is carried from your lungs by red blood cells in your bloodstream. Cells of your body use the oxygen and carbon dioxide is produced as waste, which is carried by your blood back to your lungs. You exhale and release the C02. You will study this exchange in today’s lab.

You will be using a pH indicator known as bromothymol blue. When you exhale into a baggie, the carbon dioxide will react with water in the bag. This reaction produces carbonic acid, which starts to acidify the water. More breathes in the bag equal more carbon dioxide, which equal a lower (more acidic) pH. You will notice the bromothymol will turn green when the pH of the water is right about 6.8 and it will turn yellow when the pH drops further to 6.0 and lower.

Food and air both enter your body through your mouth, diverging when they reach the esophagus and trachea. Food goes to the gastrointestinal tract through your esophagus and air travels to your lungs via the trachea, or windpipe.

You will be making a model of how your lungs work in this lab. It will include the trachea, lungs, and the diaphragm, which expands and contracts as it fills and empties your lungs.

Today you will make a calibrated, or marked, container that you will use to measure your lung capacity. You will fill the calibrated container with water, slide a hose into it, take a really deep breath, and blow in the hose. As the air in your lungs enters the container, it will push out the water inside. Just blow as long and as much as you can, then when you flip the bottle over you will be able to read the amount of water you have displaced. If you will subtract the water displaced from the total amount of water in the bottle, the result is your lung capacity.

When you exercise your body requires more oxygen in order to burn the fuel that has been stored in your muscles.  Since oxygen is moved through your body by red blood cells, exercise increases your heart rate so that the blood can be pumped through your body faster. This delivers the needed oxygen to your muscles faster. The harder you exercise, the more oxygen is needed, so your heart and blood pump even faster still.

Stethoscopes are instruments used to amplify sounds like your heartbeat. Your doctor is trained to use a stethoscope not only to count the beats, but he or she can also hear things like your blood entering and exiting the heart
and its valves opening and closing. Pretty cool!

Today you will make and test a homemade stethoscope. Even though it will be pretty simple, you should still be able to hear your heart beating and your heart pumping. You can also use it to listen to your lungs, just like your doctor does.

Did you know that your tongue can taste about 10,000 unique flavors? Our tongues take an organized approach to flavor classification by dividing tastes into the four basic categories of sweet, sour, salty, and bitter.

For this experiment, you will need a brave partner! They will be blindfolded and will be attempting to guess foods. Relying only on their sense of taste, they will try to determine what kind of foods you are giving them.

The tongue has an ingenious design. Receptors responsible for getting information are separate and compartmentalized. So, different areas on the tongue actually have receptors for different types of tastes. This helps us to separate and enjoy the distinct flavors. In this experiment, you will be locating the receptors for sweet, sour, salty, and bitter on the tongue’s surface.

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Digestion starts in your mouth as soon as you start to chew. Your saliva is full of enzymes. They are a kind of chemical key that unlock chains of protein, fat, and starch molecules. Enzymes break these chains down into smaller molecules like sugars and amino acids.

In this experiment, we will examine how the enzymes in your mouth help to break down the starch in a cracker. You will test the cracker to confirm starch content, then put it in your mouth and chew it for a long time in order to really let the enzymes do their job. Finally you will test the cracker for starch content and see what has happened as a result of your chewing.

The buildup of things like food and bacteria where your gums and teeth meet, and also between your teeth, is called plaque. Where plaque lives is also where the bacteria turns the sugar in your mouth into harmful acids that attack your teeth’s enamel and can lead to gum disease. Regular brushing is a great way to remove plaque and keep your mouth healthy.

Involuntary responses are ones that you can’t control, but they are usually in place to help with survival. One good example is when you touch something hot. Your hand does not take the time to send a message to your brain and then have the brain tell your hand to pull away. By then, your hand might be seriously hurt! Instead, your body immediately removes your hand in order to protect it from further harm.

Today you will test an involuntary reflex by using the tendon reflex test. A thick, rubbery band called the patellar tendon holds your knee cap in place. Having one leg on top of the other not only stretches the tendon, but it also makes it possible to see a reaction. You can test the reflex by giving your tendon a tap and watching what happens.

The skeleton is your body’s internal supporting structure. It holds everything together. In addition to providing support, bones act as shock absorbers when you jump, fall, and run. Bones have big responsibilities and so they must be really strong. They also need to be arranged properly for the best support and shock absorption.

In this experiment, we will look at the internal arrangement of the bones holding together your body.

Some groups of muscles are stronger than others because each group is designed for a different and specific function. It just makes sense that the muscle groups in our legs would need to be stronger than the ones in our toes.

For this experiment, you will use a bathroom scale to test the strength of various muscle groups.

In this experiment, we will continue to explore Ruffini’s endings in your skin. We also look at your body’s ability to detect temperature and regulate its own temperature. You will study how the body cools and warms itself.

Your fingers have receptors which perform various jobs. In addition to touch, they can detect pressure, texture, and other physical stimuli.  One specialized type of receptors is called Ruffini’s receptors. They are good at identifying changes in pressure and temperature. In this experiment, we will test their ability to distinguish between hot and cold temperatures. We are actually going to try and trick your Ruffini endings. Do you think it will work?

Skin has another function that it vital to your survival: temperature regulation. Being exposed to high temperatures causes your skin’s pores to open up and release sweat onto your body. This helps cool us off by the resulting process of evaporation.

Your pores will close in extremely cold temperatures. Also, the body stops blood flowing to the skin in order to conserve heat for the important vital organs and their processes.

In this lab, we study the moisture that your skin produces – even when you are not aware of it!

This lab has two parts. First, you will learn a bit about how specific chemicals react in a specific manner. And next, you will learn a bit of biology: the structure of bird bones and the minerals that compose them.

This experiment has two parts. For the first half, you will mix two chemicals that will produce heat and gas. The temperature receptors in your skin will be able to detect the heat. Your ears will detect the gas at it vibrates and escapes its container.

In the second portion you will demonstrate a characteristic in a chemical reaction. For this experiment, it will be an endothermic reaction, which is the absorption of heat energy. This type of reaction is easy to notice because it makes things cold to touch.  The chemical you will be using, ammonium nitrate, is actually used in emergency cold packs.

In addition to looking pretty neat with all those loops and whirls, your fingertips are great at multitasking. The skin on them has a ton of receptors that help us to gather a lot of information about our environment such as texture, movement, pressure, and temperature.

This experiment will test your ability to determine textures by using touch receptors. You will use shoeboxes with holes cut into them to make texture boxes. Each box will have a textured surface that you can feel, but not see. Through the receptors in your fingers, you will determine whether the surface is rough, waxy, soft, or smooth.

Did you know that the patterns on the tips of your fingers are unique? It’s true! Just like no two snowflakes are alike, no two people have the same set of fingerprints. In this experiment, you will be using a chemical reaction to generate your own set of blood-red prints.

Your body moves when muscles pull on the bones through ligaments and tendons. Ligaments attach the bones to other bones, and the tendons attach the bones to the muscles.

If you place your relaxed arm on a table, palm-side up, you can get the fingers to move by pushing on the tendons below your wrist. We’re going to make a real working model of your hand, complete with the tendons that move the fingers! Are you ready?

A pedigree analysis chart, usually used for families, allow us to visualize the inheritance of genotypes and phenotypes (traits). In this chart, the P, F1, and F2 generation are represented by the numerals I, II, and III respectively. Notice that those carrying the trait are colored red, and those not carrying the trait (the normal-looking ones) are in blue. The normal, non-trait carrying organisms on the chart are called the wild-type.

The term wild-type is used in genetics often to refer to organisms not carrying the trait being studied. For example, if we were studying a gene that turns house-flies orange, we would call the normal-looking ones the wild-type.

Let’s make a pedigree for your family. Here’s what you need:

We have done some extensive experiments on taste buds: how they are categorized, what tastes they recognize, and we have even mapped their location on your tongue. But we haven’t yet mentioned this fact: not all people can taste the same flavors!

So today we will check to see if you have a dominant or recessive gene for a distinct genetic characteristic. We’ll do this by testing your reaction to the taste of a chemical called phenylthiocarbamide (or PTC, for short). The interesting thing about PTC is that some people can taste it – and generally have a very adverse reaction. However, some people can’t taste it at all.

Why do families share similar features like eye and hair color? Why aren’t they exact clones of each other? These questions and many more will be answered as well look into the fascinating world of genetics!

Genetics asks which features are passed on from generation to generation in living things. It also tries to explain how those features are passed on (or not passed on). Which features are stay and leave depend on the genes of the organism and the environment the organism lives in. Genes are the “inheritance factors “described in Mendel’s laws. The genes are passed on from generation to generation and instruct the cell how to make proteins. A genotype refers to the genetic make-up of a trait, while phenotype refers to the physical manifestation of the trait.

We’re going to create a family using genetics!

Plants need light, water, and soil to grow. If you provide those things, you can make your own greenhouse where you can easily observe plants growing. Here’s a simple experiment on how to use the stuff from your recycling bin to make your own garden greenhouse.

We’ll first look at how to make a standard, ordinary greenhouse. Once your plants start to grow, use the second part of this experiment to track your plant growth. Once you’ve got the hang of how to make a bottle garden, then you can try growing a carnivorous greenhouse.
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As you walk around your neighborhood, you probably see many other people, as well as some birds flying around, maybe some fish swimming down a local stream, and perhaps even a lizard darting behind a bush or a frog sitting contently on top of a pond. Most likely, you know that all of these living things are animals, but they are even more closely related than that.

Unsurprisingly, often the most interesting critters found in soil are the hardest to find! They’re small, fast, and used to avoiding things that search for them. So, how do we find and study these tiny insects? With a Berlese Funnel (Also called the Tullgren funnel)!

Some insects are just too small! Even if we try to carefully pick them up with forceps, they either escape or are crushed. What to do?

Answer: Make an insect aspirator! An insect aspirator is a simple tool scientists use to collect bugs and insects that are too small to be picked up manually. Basically it’s a mini bug vacuum!

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The way animals and plants behave is so complicated because it not only depends on climate, water availability, competition for resources, nutrients available, and disease presence but also having the patience and ability to study them close-up.

We’re going to build an eco-system where you’ll farm prey stock for the predators so you’ll be able to view their behavior. You’ll also get a chance to watch both of them feed, hatch, molt, and more! You’ll observe closely the two different organisms and learn all about the way they live, eat, and are eaten.

How does salt affect plant growth, like when we use salt to de-ice snowy winter roads? How does adding fertilizer to the soil help or hurt the plants? What type of soil best purifies the water? All these questions and more can be answered by building a terrarium-aquarium system to discover how these systems are connected together.

What grows in the corner of your windowsill? In the cracks in the sidewalk? Under the front steps? In the gutter at the bottom of the driveway? Specifically, how  doe these animals build their homes and how much space do they need? What do they eat? Where do fish get their food? How do ants find their next meal?

These are hard questions to answer if you don’t have a chance to observe these animals up-close. By building an eco-system, you’ll get to observe and investigate the habits and behaviors of your favorite animals. This column will have an aquarium section, a decomposition chamber with fruit flies or worms, and a predator chamber, with water that flows through all sections. This is a great way to see how the water cycle, insects, plants, soil, and marine animals all work together and interact.

When birds and animals drink from lakes, rivers, and ponds, how pure it is? Are they really getting the water they need, or are they getting something else with the water?

This is a great experiment to see how water moves through natural systems. We’ll explore how water and the atmosphere are both polluted and purified, and we’ll investigate how plants and soil help with both of these. We’ll be taking advantage of capillary action by using a wick to move the water from the lower aquarium chamber into the upper soil chamber, where it will both evaporate and transpire (evaporate from the leaves of plants) and rise until it hits a cold front and condenses into rain, which falls into your collection bucket for further analysis.

Sound complicated? It really isn’t, and the best part is that it not only uses parts from your recycling bin but also takes ten minutes to make.

Mass and energy are conserved. This means you can’t create or destroy them, but you can change their location or form.

Most people don’t understand that the E energy term means all the energy transformations, not just the nuclear energy.

The energy could be burning gasoline, fusion reactions (like in the sun), metabolizing your lunch, elastic energy in a stretched rubber band… every kind of energy stored in the mass is what E stands for.

For example, if I were to stretch a rubber band and somehow weigh it in the stretched position, I would find it weighed slightly more than in the unstretched position.

Why? How can this be? I didn’t add any more particles to the system – I simply stretched the rubber band. I added energy to the system, which was stored in the electromagnetic forces inside the rubber band, which add to the mass of the object (albeit very slightly). Read more about this in Unit 7: Lesson 3.

Photosynthesis is a process where light energy is changed into chemical energy.  As we said in the last section, this process happens in the chloroplast of plant cells.  Photosynthesis is one of the most important things that happen in cells.

In fact, photosynthesis is considered one of the most important processes for all life on Earth.  It makes sense that photosynthesis is really important to plants, since it gives them energy, but why is it so important to animals?  Let’s learn a little more about photosynthesis and see if we can answer that question.

There are many steps to photosynthesis, but if we wanted to sum it up in one equation, it would be carbon dioxide (CO₂) + water (H₂O) makes glucose (C₆H₁₂O₆) and oxygen (O₂).  These words can be written like this:

In eukaryotes there is a nucleus, so a more complex process called mitosis is needed with cell division. Mitosis is divided into four parts, or phases:

Phase 1 – Prophase: In this phase the nuclear membrane begins to break down and the DNA forms structures called chromosomes.

Phase 2 – Metaphase: In this phase the chromosomes line up along the center of the parent cell

Phase 3 – Anaphase: In this phase, the chromosomes break apart, with a complete set of DNA going to each side of the cell

Phase 4 – Telophase: In this phase, a new nuclear membrane forms around each of the sets of DNA

The four stages of mitosis (the cell at the top has not started mitosis) lead to two daughter cells.

A little after telophase, the cytoplasm splits and a new cell membrane forms.  Once again, two daughter cells have formed.  Take a look at this animation for a good overview of mitosis and see if you can identify all the phases.

Here’s a fun experiment that shows you how much stuff can pass through a membrane. Scientist call it the  semi-permeability of membranes.

Before we start, take out your science journal and answer this question: What do you think will happen when we stick a piece of celery into a glass of regular water. Anything special?

What if we add a teaspoon of salt to the water? Now do you think anything will happen?
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The carrot itself is a type of root—it is responsible for conducting water from the soil to the plant. The carrot is made of cells. Cells are mostly water, but they are filled with other substances too (organelles, the nucleus, etc).

We’re going to do two experiments on a carrot: first we’re going to figure out how to move water into the cells of a carrot. Second, we’ll look at how to move water within the carrot and trace it. Last, we’ll learn how to get water to move out of the carrot. And all this has to do with cells!

One way substances can get into a cell is called passive transport. One special kind of passive transport is osmosis, when water crosses into the cell. This experiment allows you to see the process of osmosis in action. Are you ready?

If you think of celery as being a bundle of thin straws, then it’s easy to see how this experiment works. In this activity, you will get water to creep up through the plant tissue (the celery stalk) and find out how to make it go faster and slower.

The part of the celery we eat is the stalk of the plant.  Plant stalks are designed to carry water to the leaves, where they are needed for the plant to survive.  The water travels up the celery as it would travel up any plant.

This experiment allows you to see protozoa, tiny-single celled organisms, in your compound microscope. While I can go in my backyard and find a lot of interesting pond scum and dead insects, I realize that not everybody has a thriving ecosystem on hand, especially if you live in a city.

I am going to show you how to grow a protozoa habitat that you can keep in a window for months (or longer!) using a couple of simple ingredients.

Once you have a protist farm is up and running, you’ll be able to view a sample with your compound microscope. If you don’t know how to prepare a wet mount or a heat fix, you’ll want to review the microscope lessons here.

Protozoa are protists with animal-like behaviors. Protists live in almost any liquid water environment. Some protists are vital to the ecosystem while others are deadly.

If the cell has a nucleus, the DNA is located in the nucleus.  If not, it is found in the cytoplasm.  DNA is the genetic material that has all the information about a cell.

DNA is a long molecule found in the formed by of two strands of genes. DNA carries two copies—two “alleles”—of each gene. Those alleles can either be similar to each other (homozygous), or dissimilar (heterozygous).

We’re going to learn how to extract DNA from any fruit or vegetable you have lying around the fridge. Are you ready?

Cells make up every living thing. Take a look at all the living things you can see just in your house. You can start off with you and your family. If you have any pets, be sure to include them. Don’t forget about houseplants as well – they’re alive. Now take a walk outside. You’ll likely see many more plants, as well as animals like birds and insects. Now imagine if all those living things were gone. That’s how it would be if there were no cells, because cells are what all those living things are made of.

Animals, plants and other living things look different, and contain many different kinds of cells, but when you get down to it, all of us are just a bunch of cells – and that makes cells pretty much the most important thing when it comes to life!

Hans Lippershey was the first to peek through his invention of the refractor telescope in 1608, followed closely by Galileo (although Galileo used his telescope for astronomy and Lippershey’s was used for military purposes).  Their telescopes used both convex and concave lenses.

A few years later, Kepler swung into the field and added his own ideas: he used two convex lenses (just like the ones in a hand-held magnifier), and his design the one we still use today. We’re going to make a simple microscope and telescope using two lenses, the same way Kepler did.  Only our lenses today are much better quality than the ones he had back then!

You can tell a convex from a concave lens by running your fingers gently over the surface – do you feel a “bump” in the middle of your hand magnifying lens?  You can also gently lay the edge of a business card (which is very straight and softer than a ruler) on the lens to see how it doesn’t lay flat against the lens.

Your magnifier has a convex lens – meaning the glass (or plastic) is thicker in the center than around the edges.  The image here shows how a convex lens can turn light to a new direction using refraction. You can read more about refraction here.

A microscope is very similar to the refractor telescope with one simple difference – where you place the focus point.  Instead of bombarding you with words, let’s make a microscope right now so you can see for yourself how it all works together. Are you ready?